Clinical Trial Management Process

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A Clinical Trial Management Process is a clinical study process that manages clinical trials.



References

2021

2016

2015

  • (Gupta et al., 2015) ⇒ Anjali Gupta, Karen J. Calfas, Simon J. Marshall, Thomas N. Robinson, Cheryl L. Rock, Jeannie S. Huang, Melanie Epstein-Corbin et al. (2015). “Clinical Trial Management of Participant Recruitment, Enrollment, Engagement, and Retention in the SMART Study Using a Marketing and Information Technology (MARKIT) Model.” Contemporary Clinical Trials, 42
    • ABSTRACT: Advances in information technology and near ubiquity of the Internet have spawned novel modes of communication and unprecedented insights into human behavior via the digital footprint. Health behavior randomized controlled trials (RCTs), especially technology-based, can leverage these advances to improve the overall clinical trials management process and benefit from improvements at every stage, from recruitment and enrollment to engagement and retention. In this paper, we report the results for recruitment and retention of participants in the SMART study and introduce a new model for clinical trials management that is a result of interdisciplinary team science. The MARKIT model brings together best practices from information technology, marketing, and clinical research into a single framework to maximize efforts for recruitment, enrollment, engagement, and retention of participants into a RCT. These practices may have contributed to the study's on-time recruitment that was within budget, 86% retention at 24 months, and a minimum of 57% engagement with the intervention over the 2-year RCT. Use of technology in combination with marketing practices may enable investigators to reach a larger and more diverse community of participants to take part in technology-based clinical trials, help maximize limited resources, and lead to more cost-effective and efficient clinical trial management of study participants as modes of communication evolve among the target population of participants.