Molecular Interaction Database

The Molecular Interaction Database is a Genomic Database.

• AKA: MINT----

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References

2009

• (Cusick et al., 2009) ⇒ Michael E Cusick, Haiyuan Yu, Alex Smolyar, Kavitha Venkatesan, Anne-Ruxandra Carvunis, Nicolas Simonis, Jean-François Rual, Heather Borick, Pascal Braun, Matija Dreze, Jean Vandenhaute, Mary Galli, Junshi Yazaki, David E Hill, Joseph R Ecker, Frederick P Roth, and Marc Vidal. (2009). “Literature-Curated Protein Interaction Datasets.” In: Nature Methods 6, 39 - 46 (2009)
  • Manual curation of protein interactions from literature began with pioneering curation for the yeast Saccharomyces cerevisiae by the Yeast Proteome Database (YPD)13. Those early efforts demonstrated that effective curation was possible and also broadly aimed to capture all types of functional and genomic information, not only PPIs. Genomic databases dedicated to a single model organism arose in parallel with genome sequencingprojects, for example, the Saccharomyces Genome Database (SGD)14 and The Arabidopsis Information Resource (TAIR)15. Although initially devoted to sequence information, many of these databases eventually added many types of literature-curated information, including PPI data. In time, the publications reporting PPIs exceeded the capacity of specialized genome databases and led to the creation of databases dedicated to PPIs, for example, the Munich Information Center for Protein Sequence (MIPS) protein interaction database16, the Biomolecular Interaction Network Database (BIND)17, the Database of Interacting Proteins (DIP)18, the Molecular Interaction database (MINT)19 and the protein Interaction database (IntAct)20. More recent PPI curation efforts, the Biological General Repository for Interaction Datasets (BioGRID)21 and the Human Protein Reference Database (HPRD)22, have attempted larger-scale curation of data from more manuscripts and more interactions.

2007

• Chatr-aryamontri, A. et al. (2007). “MINT: the Molecular INTeraction database.” In: Nucleic Acids Res. 35, D572–D574.

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