2009 GenomeAndProteomeAnnotation
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- (Reeves et al., 2009) ⇒ Gabrielle A Reeves, David Talavera, Janet M Thornton. (2009). “Genome and Proteome Annotation: Organization, Interpretation and Integration.” In: [[journal::J R Soc Interface], 6(31).
Subject Headings: Genomic Database, Proteomic Database, Survey, Curated Data, Annotation System.
Quotes
= Abstract
- Recent years have seen a huge increase in the generation of genomic and proteomic data. This has been due to improvements in current biological methodologies, the development of new experimental techniques and the use of computers as support tools. All these raw data are useless if they cannot be properly analysed, annotated, stored and displayed. Consequently, a vast number of resources have been created to present the data to the wider community. Annotation tools and databases provide the means to disseminate these data and to comprehend their biological importance. This review examines the various aspects of annotation: type, methodology and availability. Moreover, it puts a special interest on novel annotation fields, such as that of phenotypes, and highlights the recent efforts focused on the integrating annotations.
6. Conclusions
- Given the plethora of annotation tools that have been developed over the past few years (figure 1 and table 1), the next goal has been to try to find ways in which the information that these annotation tools provides can be integrated. This has begun to be achieved with the advent of tools to help infrastructure (DAS, Web services and widgets) and increased funding into integrative projects (such as e-Protein and BioSapiens). To further this, we need to extend our collaborations between the genomic and proteomic disciplines.
References
| Author | volume | Date Value | title | type | journal | titleUrl | doi | note | year | |
|---|---|---|---|---|---|---|---|---|---|---|
| 2009 GenomeAndProteomeAnnotation | Gabrielle A Reeves David Talavera Janet M Thornton | Genome and Proteome Annotation: Organization, Interpretation and Integration | http://dx.doi.org/10.1098/rsif.2008.0341 | 10.1098/rsif.2008.0341 |