Ligand
A Ligand is a simple biomolecule (functional group) that binds to a central metal atom to form a coordination complex.
References
2023
- HTTP://chat.openai.com/chat
- A ligand is a molecule that binds to and forms a complex with a larger biomolecule, often a protein. Ligands can be atoms, ions, or molecules, and are usually characterized by their ability to bind to a specific site on a target protein, such as an enzyme or receptor. Ligands can be endogenous (produced naturally in the body) or exogenous (introduced into the body from an external source).
Related concepts include:
- Agonist: a type of ligand that activates a receptor by mimicking the effects of an endogenous ligand.
- Antagonist: a type of ligand that binds to a receptor without activating it, blocking the action of endogenous ligands or other agonists.
- Enzyme inhibitor: a type of ligand that binds to an enzyme, blocking its activity.
- Substrate: a type of ligand that binds to an enzyme and undergoes a chemical reaction.
- Receptor: a large protein molecule that binds to a ligand and initiates a cellular response.
- A ligand is a molecule that binds to and forms a complex with a larger biomolecule, often a protein. Ligands can be atoms, ions, or molecules, and are usually characterized by their ability to bind to a specific site on a target protein, such as an enzyme or receptor. Ligands can be endogenous (produced naturally in the body) or exogenous (introduced into the body from an external source).
2023
- (Wikipedia, 2023) ⇒ https://en.wikipedia.org/wiki/ligand Retrieved:2023-2-27.
- In coordination chemistry, a ligandis an ion or molecule (functional group) that binds to a central metal atom to form a coordination complex. The bonding with the metal generally involves formal donation of one or more of the ligand's electron pairs, often through Lewis bases. [1] The nature of metal–ligand bonding can range from covalent to ionic. Furthermore, the metal–ligand bond order can range from one to three. Ligands are viewed as Lewis bases, although rare cases are known to involve Lewis acidic "ligands".
Metals and metalloids are bound to ligands in almost all circumstances, although gaseous "naked" metal ions can be generated in a high vacuum. Ligands in a complex dictate the reactivity of the central atom, including ligand substitution rates, the reactivity of the ligands themselves, and redox. Ligand selection requires critical consideration in many practical areas, including bioinorganic and medicinal chemistry, homogeneous catalysis, and environmental chemistry.
Ligands are classified in many ways, including: charge, size (bulk), the identity of the coordinating atom(s), and the number of electrons donated to the metal (denticity or hapticity). The size of a ligand is indicated by its cone angle.
- In coordination chemistry, a ligandis an ion or molecule (functional group) that binds to a central metal atom to form a coordination complex. The bonding with the metal generally involves formal donation of one or more of the ligand's electron pairs, often through Lewis bases. [1] The nature of metal–ligand bonding can range from covalent to ionic. Furthermore, the metal–ligand bond order can range from one to three. Ligands are viewed as Lewis bases, although rare cases are known to involve Lewis acidic "ligands".
- ↑ Burdge, J., & Overby, J. (2020). Chemistry – Atoms first (4th ed.). New York, NY: McGraw Hill. doi:9781260571349