Clinical Study Database

A Clinical Trials Registry is a clinical study database of clinical trials.

• Context:
  • It can range from being a Clinical Trials Registry to being a Observational Clinical Study Registry.
  • …
• Example(s):
  • ClinicalTrials.gov Registry.
  • WHO International Clinical Trials Registry Platform (ICTRP).
  • EudraCT (European Union Drug Regulating Authorities Clinical Trials).
  • Aggregate Analysis of ClinicalTrials.gov (AACT) Database.
  • …
• Counter-Example(s):
  • a Preclinical Research Registry (for preclinical research).
• See: Preregistration (Science), Clinical Trial Registration, International Committee of Medical Journal Editors.

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References

2021

• (Wikipedia, 2021) ⇒ https://en.wikipedia.org/wiki/Preregistration_(science)#Clinical_trial_registration Retrieved:2021-12-23.
  • Clinical trial registration is the practice of documenting clinical trials before they are performed in a clinical trials registry so as to combat publication bias and selective reporting. Registration of clinical trials is required in some countries and is increasingly being standardized. Some top medical journals will only publish the results of trials that have been pre-registered. A clinical trials registry is a platform which catalogs registered clinical trials. ClinicalTrials.gov, run by the United States National Library of Medicine (NLM) was the first online registry for clinical trials, and remains the largest and most widely used. In addition to combating bias, clinical trial registries serve to increase transparency and access to clinical trials for the public. Clinical trials registries are often searchable (e.g. by disease/indication, drug, location, etc.). Trials are registered by the pharmaceutical, biotech or medical device company (Sponsor) or by the hospital or foundation which is sponsoring the study, or by another organization, such as a contract research organization (CRO) which is running the study. There has been a push from governments and international organizations, especially since 2005, to make clinical trial information more widely available and to standardize registries and processes of registering. The World Health Organization is working toward "achieving consensus on both the minimal and the optimal operating standards for trial registration".

2021

• (Wikipedia, 2021) ⇒ https://en.wikipedia.org/wiki/Preregistration_(science)#Overview_of_clinical_trial_registries Retrieved:2021-12-23.
  • Worldwide, there is growing number of registries. A 2013 study identified the following top five registries (numbers updated as of August 2013):

1.	ClinicalTrials.gov	150,551
2.	EU register	21,060
3.	Japan registries network (JPRN)	12,728
4.	ISRCTN	11,794
5.	Australia and New Zealand (ANZCTR)	8,216

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