Serotonin Receptor
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A Serotonin Receptor is a G Protein-Coupled Receptor that ...
- AKA: 5-HT Receptor.
- See: Caenorhabditis Elegans, G Protein-Coupled Receptor, Ligand-Gated Ion Channel, Central Nervous System, Peripheral Nervous System, Neurotransmitter, Synaptic Transmission, Serotonin, Neurotransmitter, Ligand (Biochemistry), Glutamic Acid, Gamma-Aminobutyric Acid, Lorcaserin.
References
2018
- (Wikipedia, 2018) ⇒ https://en.wikipedia.org/wiki/5-HT_receptor Retrieved:2018-8-27.
- 5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission. The serotonin receptors are activated by the neurotransmitter serotonin, which acts as their natural ligand. The serotonin receptors modulate the release of many neurotransmitters, including glutamate, GABA, dopamine, epinephrine / norepinephrine, and acetylcholine, as well as many hormones, including oxytocin, prolactin, vasopressin, cortisol, corticotropin, and substance P, among others. The serotonin receptors influence various biological and neurological processes such as aggression, anxiety, appetite, cognition, learning, memory, mood, nausea, sleep, and thermoregulation. The serotonin receptors are the target of a variety of pharmaceutical and recreational drugs, including many antidepressants, antipsychotics, anorectics, antiemetics, gastroprokinetic agents, antimigraine agents, hallucinogens, and entactogens. Serotonin receptors are found in almost all animals and are even known to regulate longevity and behavioral aging in the primitive nematode, Caenorhabditis elegans.