Psoriasis
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A Psoriasis is an autoimmune skin ailment characterized by skin plaques.
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- Counter-Example(s):
- Counter-Example(s):
- See: Dermatology, Erythema, Psoriatic Arthritis, Methotrexate, Psoriasis Symptom Inventory (PSI) PRO.
References
2022
- (Wikipedia, 2022) ⇒ https://en.wikipedia.org/wiki/Psoriasis Retrieved:2022-3-1.
- Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by raised areas of abnormal skin. These areas are red, or purple on some people with darker skin, dry, itchy, and scaly. Psoriasis varies in severity from small, localized patches to complete body coverage. Injury to the skin can trigger psoriatic skin changes at that spot, which is known as the Koebner phenomenon. The five main types of psoriasis are plaque, guttate, inverse, pustular, and erythrodermic. Plaque psoriasis, also known as psoriasis vulgaris, makes up about 90% of cases. It typically presents as red patches with white scales on top. Areas of the body most commonly affected are the back of the forearms, shins, navel area, and scalp. Guttate psoriasis has drop-shaped lesions. Pustular psoriasis presents as small, noninfectious, pus-filled blisters. Inverse psoriasis forms red patches in skin folds. Erythrodermic psoriasis occurs when the rash becomes very widespread, and can develop from any of the other types. Fingernails and toenails are affected in most people with psoriasis at some point in time. This may include pits in the nails or changes in nail color. Psoriasis is generally thought to be a genetic disease that is triggered by environmental factors. If one twin has psoriasis, the other twin is three times more likely to be affected if the twins are identical than if they are nonidentical. This suggests that genetic factors predispose to psoriasis. Symptoms often worsen during winter and with certain medications, such as beta blockers or NSAIDs. Infections and psychological stress can also play a role. The underlying mechanism involves the immune system reacting to skin cells. Diagnosis is typically based on the signs and symptoms. There is no known cure for psoriasis, but various treatments can help control the symptoms. These treatments include steroid creams, vitamin D3 cream, ultraviolet light, and immunosuppressive drugs, such as methotrexate. About 75% of skin involvement improves with creams alone. The disease affects 2–4% of the population. Men and women are affected with equal frequency. The disease may begin at any age, but typically starts in adulthood. Psoriasis is associated with an increased risk of psoriatic arthritis, lymphomas, cardiovascular disease, Crohn's disease, and depression. Psoriatic arthritis affects up to 30% of individuals with psoriasis. The word "psoriasis" is from Greek ψωρίασις, meaning "itching condition" or "being itchy" from psora, "itch", and -iasis, "action, condition".
2021
- https://www.coskincare.com/blog/how-do-you-get-plaque-psoriasis
- QUOTE: ... Plaque psoriasis is one of the most common forms of the condition, making up around 90% of all cases. Plaque psoriasis is an autoimmune disease where the skin’s cells build up rapidly, creating dry and itchy patches or scales on the body. Though the underlying cause of this condition is still unknown, specific factors such as stress, smoking, and obesity can trigger an outbreak.
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- QUOTE: ... Plaque psoriasis is one of the most common forms of the condition, making up around 90% of all cases. Plaque psoriasis is an autoimmune disease where the skin’s cells build up rapidly, creating dry and itchy patches or scales on the body. Though the underlying cause of this condition is still unknown, specific factors such as stress, smoking, and obesity can trigger an outbreak.
2019
- (Nao et al., 2019) ⇒ Chan H. Nao, Janice Chung, and Eric L. Simpson. (2019). “Quality of Life and Disease Impact of Atopic Dermatitis and Psoriasis on Children and their Families.” Children 6, no. 12
- QUOTE: Atopic dermatitis (AD) and psoriasis are common chronic skin diseases affecting children. These disorders negatively impact the quality of life (QoL) of patients in health-related aspects such as physical, psychosocial, and mental functioning. ...
- QUOTE: Atopic dermatitis (AD) and psoriasis are common chronic skin diseases affecting children. These disorders negatively impact the quality of life (QoL) of patients in health-related aspects such as physical, psychosocial, and mental functioning. ...
2017
- (Furue & Kadono, 2017) ⇒ Masutaka Furue, and Takafumi Kadono. (2017). ““Inflammatory Skin March” in Atopic Dermatitis and Psoriasis.” Inflammation Research 66, no. 10
- QUOTE: ... Inflammatory skin diseases such as atopic dermatitis and psoriasis are an active source of diverse proinflammatory cytokines and chemokines, which are readily detectable in the circulation and are likely to be involved in developing comorbidities.
Evidence: Both atopic dermatitis and psoriasis are frequently comorbid with CVD, metabolic syndrome and autoimmune diseases, the consequence of which is called “inflammatory skin march”, “psoriatic march” or “march of psoriasis”. ...
- QUOTE: ... Inflammatory skin diseases such as atopic dermatitis and psoriasis are an active source of diverse proinflammatory cytokines and chemokines, which are readily detectable in the circulation and are likely to be involved in developing comorbidities.