Pertussis Toxin
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A Pertussis Toxin is a multimeric protein composed of five subunits S1 - S5. S1 contains mono ADPribose Transferase
- Context:
- It can (typically) be a Virulence Factor produced by Bordetella Pertussis.
- Example(s):
- Bordetella Pertussis http://www.uniprot.org/uniprot/P04977
- Bordetella pertussis http://www.uniprot.org/uniprot/Q7VSX5
- PMID 4960932: “Pertussis toxin of Bordetella pertussis is secreted by a type IV secretion system comprised of the products of the nine ptl (pertussis toxin liberation ) genes . These proteins are believed to form a complex spanning both the inner and outer membranes and passing through the peptidoglycan layer .”
- See: Bordetella Pertussis.
References
2009
- (Wikipedia, 2009) ⇒ http://en.wikipedia.org/wiki/Pertussis_toxin
- Pertussis toxin (PT) is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis,[1] which causes whooping cough. PT is involved in the colonization of the respiratory tract and the establishment of infection. [2] Research suggests PT may have a therapeutic role in treating a number of common human ailments including hypertension,[3] viral inhibition,[4] and autoimmune inhibition. [5]