Periplasmic Space

A Periplasmic Space is a membrane space between the Inner Membrane and the Outer Membrane of a Cell.

• Example(s):
  • a Gram-Negative Bacteria Periplasm.
  • a Gram-Positive Bacteria Periplasm.
  • a Fungi Periplasm.
• See: Cellular Component.

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References

2009a

• (Wikipedia, 2009) ⇒ http://en.wikipedia.org/wiki/Periplasm
  • The periplasmic space or periplasm is a space between the inner cytoplasmic membrane and external outer membrane of Gram-negative bacteria or the equivalent space between the cell membrane and cell wall in Gram-positive bacteria. It may constitute up to 40% of the total cell volume in Gram-negative species, and is drastically smaller in Gram-positive. [1]
  • The space contains a loose network of murein (peptidoglycan) chains, as well as a gel containing hydrolytic and degradative enzymes. [2] Other enzymes in the gel are involved in various biochemical pathways including peptidoglycan synthesis, electron transport, and alteration of substances toxic to the cell (xenobiotic metabolism). [3] In some species, the gel also contains beta-lactamase, an enzyme responsible for degrading penicillin. This can be of clinical importance when considering antibiotic resistance.

2009b

• Gene Ontology http://amigo.geneontology.org/cgi-bin/amigo/term-details.cgi?term=GO:0042597&session_id=5828amigo1240506945
  • Accession: GO:0042597
  • Ontology: cellular component
  • Synonyms
    • exact: periplasm
    • alt_id: GO:0005620
  • Definition
    • The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or inner membrane and cell wall (Fungi). [source: GOC:go_curators].

2009c

• MeSH:A.11.284.295.680
  • “The space between the inner and outer membranes of a cell that is shared with the cell wall."

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