National Cancer Institute Thesaurus (NCIt)

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An National Cancer Institute Thesaurus (NCIt) is a healthcare thesaurus produced by NCI.

  • Context:
    • It can feature:
      • Stable, unique codes for biomedical concepts;
      • Preferred terms, synonyms, research codes, external source codes, and other information;
      • Over 100,000 textual definitions;
      • Links to NCI Metathesaurus and other information sources;
      • Over 500,000 cross-links between concepts, providing formal logic-based definition of many concepts;
      • Extensive content integrated from NCI and other partners, much available as separate NCIt subsets
      • Updated frequently by a team of subject matter experts.
    • …
  • Example(s):
  • Counter-Example(s):
  • See: Basic Clinical Research, UMLS Metathesaurus, Electronic Thesaurus.

References

2022

2020

  • https://ncithesaurus.nci.nih.gov/ncitbrowser/
    • QUOTE: ... NCI Thesaurus (NCIt) provides reference terminology for many NCI and other systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.
    • NCIt features:
      • Stable, unique codes for biomedical concepts;
      • Preferred terms, synonyms, research codes, external source codes, and other information;
      • Over 100,000 textual definitions;
      • Links to NCI Metathesaurus and other information sources;
      • Over 500,000 cross-links between concepts, providing formal logic-based definition of many concepts;
      • Extensive content integrated from NCI and other partners, much available as separate NCIt subsets
      • Updated frequently by a team of subject matter experts.

2009

2007

2004

  • (Fragoso et al., 2004) ⇒ Gilberto Fragoso, Sherri de Coronado, Margaret Haber, Frank Hartel, and Larry Wright. (2004). “Overview and Utilization of the NCI Thesaurus.” Comparative and functional genomics 5, no. 8
    • ABSTRACT: The NCI Thesaurus is a reference terminology covering areas of basic and clinical science, built with the goal of facilitating translational research in cancer. It contains nearly 110,000 terms in approximately 36,000 concepts, partitioned in 20 sub-domains, which include diseases, drugs, anatomy, genes, gene products, techniques, and biological processes, among others, all with a cancer-centric focus in content, and originally designed to support coding activities across the National Cancer Institute. Each concept represents a unit of meaning and contains a number of annotations, such as synonyms and preferred name, as well as annotations such as textual definitions and optional references to external authorities. In addition, concepts are modelled with description logic (DL) and defined by their relationships to other concepts; there are currently approximately 90 types of named relations declared in the terminology. The NCI Thesaurus is produced by the Enterprise Vocabulary Services project, a collaborative effort between the NCI Center for Bioinformatics and the NCI Office of Communications, and is part of the caCORE infrastructure stack (http://ncicb.nci.nih.gov/NCICB/core). It can be accessed programmatically through the open caBIO API and browsed via the web (http://nciterms.nci.nih.gov). A history of editing changes is also accessible through the API. In addition, the Thesaurus is available for download in various file formats, including OWL, the web ontology language, to facilitate its utilization by others.
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