Membrane Bound Organelle
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Membrane Bound Organelle is an Organized structure of distinctive Morphology and function, bounded by a Single Or Double Lipid Bilayer Membrane and occurring within the Cell. Includes the Nucleus, Mitochondria, Plastids, Vacuoles, and Vesicles.
- AKA: Biological Membrane.
- Context:
- It seperetes Amphipathic Layer that acts as a Barrier within.
- Example(s):
- Bradyrhizobium Japonicum http://www.uniprot.org/uniprot/Q59207
- Rhizobium Meliloti http://www.uniprot.org/uniprot/P18396
- Pseudomonas Aeruginosa http://www.uniprot.org/uniprot/Q9I574
- PMID 6249740: “The quantity of membrane-bound and extracellular exotoxin A in four strains of Pseudomonas aeruginosa was investigated.”
- PMID 8386371: “We report the discovery of a Bradyrhizobium japonicum gene cluster (fixNOQP ) in which mutations resulted in defective soybean root-nodule bacteroid development and symbiotic nitrogen fixation . The predicted, DNA-derived protein sequences suggested that FixN is a heme b and copper-binding oxidase subunit, FixO a monoheme cytochrome c, FixQ a polypeptide of 54 amino acids, and FixP a diheme cytochrome c and that they are all membrane-bound .”
- Counter-Example(s):
- PMID 10361306: “The napEDABC locus coding for the periplasmic nitrate reductase of Thiosphaera pantotropha has been cloned and sequenced . The large and small subunits of the enzyme are coded by napA and napB . The sequence of NapA indicates that this protein binds the GMP-conjugated form of the molybdopterin cofactor .Cysteine-181 is proposed to ligate the molybdenum atom .It is inferred that the active site of the periplasmic nitrate reductase is structurally related to those of the molybdenum-dependent formate dehydrogenases and bacterial assimilatory nitrate reductases, but is distinct from that of the membrane-bound respiratory nitrate reductases .”
- See: Mitochondria, Nucleus.
References
2009
- (Wikipedia, 2009) ⇒ http://en.wikipedia.org/wiki/Membrane-bound
- A biological membrane or biomembrane is an enclosing or separating amphipathic layer that acts as a barrier within or around a cell. It is, almost invariably, a lipid bilayer, composed of a double layer of lipid (usually phospholipid) molecules and proteins that may constitute close to 50% of membrane content. [1]
- Gene Ontology http://amigo.geneontology.org/cgi-bin/amigo/term-details.cgi?term=GO:0043227&session_id=4446amigo1247242904
- Accession: GO:0043227
- Ontology: molecular function
- Synonyms
- exact: membrane-enclosed organelle
- Definition
- Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. [source: GOC:go_curators]