Influenza A Subtype H1N1 Virus
An Influenza A Subtype H1N1 Virus is an Influenza A virus.
References
2020
- (Wikipedia, 2020) ⇒ https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H1N1 Retrieved:2020-3-25.
- Influenza A virus subtype H1N1 (A/H1N1) is the subtype of influenza A virus that was the most common cause of human influenza (flu) in 2009, and is associated with the 1918 outbreak known as the Spanish flu.
It is an orthomyxovirus that contains the glycoproteins haemagglutinin and neuraminidase. For this reason, they are described as H1N1, H1N2 etc. depending on the type of H or N antigens they express with metabolic synergy. Haemagglutinin causes red blood cells to clump together and binds the virus to the infected cell. Neuraminidase is a type of glycoside hydrolase enzyme which helps to move the virus particles through the infected cell and assist in budding from the host cells. Some strains of H1N1 are endemic in humans and cause a small fraction of all influenza-like illness and a small fraction of all seasonal influenza. H1N1 strains caused a small percentage of all human flu infections in 2004–2005. Other strains of H1N1 are endemic in pigs (swine influenza) and in birds (avian influenza). In June 2009, the World Health Organization (WHO) declared the new strain of swine-origin H1N1 as a pandemic. This novel virus spread worldwide and had caused 18,500 laboratory-confirmed deaths with an estimated 151,700 to 575,400 deaths total by August of 2010. On 10 August 2010, the World Health Organization declared the H1N1 influenza pandemic over, saying worldwide flu activity had returned to typical seasonal patterns.
- Influenza A virus subtype H1N1 (A/H1N1) is the subtype of influenza A virus that was the most common cause of human influenza (flu) in 2009, and is associated with the 1918 outbreak known as the Spanish flu.