Inflammation Response
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An Inflammation Response is a biological response of body tissues to harmful stimuli (such as pathogens, damaged cells, or irritants).
- Context:
- It can (often) be a Protective Response (involving immune cells, blood vessels, and molecular mediators).
- It can play a crucial role in a Body's Defense Mechanisms and Tissue Repair Processes.
- Example(s):
- Skin Inflammation, such as Stomatitis.
- Arthritis.
- Bronchitis.
- ...
- Counter-Example(s):
- A Fever Response is a biological response that differs from inflammation. While inflammation typically involves localized tissue reactions, fever is a systemic response characterized by an elevated body temperature.
- See: Eosinophilia, Pathogens, Immune Cells, Blood Vessels, Cardinal Sign (Pathology), Functio Laesa, Innate Immune System, Adaptive Immune System, Hay Fever, Periodontal Disease, Atherosclerosis, Systemic Inflammatory Response Syndrome (SIRS).
References
2020
- (Wikipedia, 2020) ⇒ https://en.wikipedia.org/wiki/Inflammation Retrieved: 2020-3-25.
- Inflammation is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. It involves the activation of immune cells, blood vessels, and molecular mediators. The primary function of inflammation is to eliminate the initial cause of cell injury, clear out necrotic cells and damaged tissues, and initiate tissue repair.
- The five classical signs of inflammation are heat, pain, redness, swelling, and loss of function. Inflammation is a generic response and is considered as a mechanism of innate immunity. Insufficient inflammation can lead to progressive tissue destruction, while chronic inflammation is associated with various diseases.
- Inflammation can be classified as either acute or chronic. Acute inflammation is the initial response of the body to harmful stimuli, involving increased movement of plasma and leukocytes (especially granulocytes) from the blood into the injured tissues. Chronic inflammation involves a progressive shift in the type of cells present at the site of inflammation and is characterized by simultaneous tissue destruction and healing.
- It is important to differentiate inflammation from infection. Infection describes the interaction between microbial invasion and the body's inflammatory response, while inflammation refers to the body's immunovascular response. However, the two are often correlated, and words ending in "-itis" (referring to inflammation) are sometimes informally described as referring to infection. Differentiating between inflammation and infection is useful in pathology and medical diagnosis.
- Examples of conditions related to inflammation include hay fever, periodontal disease, atherosclerosis, and osteoarthritis. Inflammation is also associated with autoimmune diseases and type III hypersensitivity reactions.