G Protein-coupled Receptor

A G Protein-coupled Receptor is an Eukaryote Organism Protein (transmembrane receptor) that sense Molecules outside the Cell and activate Inside Signal Transduction Pathways and, ultimately, Cellular Responses.

• AKA: GPCR.
• See: GPCRDB.

---

---

References

• (Wikipedia, 2009) ⇒ http://en.wikipedia.org/wiki/G_protein-coupled_receptor
  • G protein-coupled receptors (GPCRs), also known as seven transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein-linked receptors (GPLR), comprise a large protein family of transmembrane receptors that sense molecules outside the cell and activate inside signal transduction pathways and, ultimately, cellular responses. G protein-coupled receptors are found only in eukaryotes, including yeast, plants, choanoflagellates,[1] and animals. The ligands that bind and activate these receptors include light-sensitive compounds, odors, pheromones, hormones, and neurotransmitters, and vary in size from small molecules to peptides to large proteins. G protein-coupled receptors are involved in many diseases, and are also the target of around half of all modern medicinal drugs.

---