Fluoroquinolone
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A Fluoroquinolone is a broad-spectrum antibiotic that inhibits bacterial DNA synthesis and is used to treat a variety of bacterial infections.
- Context:
- It can (typically) be used to treat Respiratory Tract Infections, Urinary Tract Infections, and Skin Infections.
- It can (often) be prescribed for Gastrointestinal Infections and Bone and Joint Infections.
- It can range from being a First-Generation Fluoroquinolone to being a Fourth-Generation Fluoroquinolone.
- It can inhibit bacterial DNA gyrase and topoisomerase IV, which are essential for bacterial DNA replication and repair.
- It can cause side effects such as Tendinitis, Tendon Rupture, and Peripheral Neuropathy.
- It can lead to Antibiotic Resistance if overused or misused.
- It can interact with other medications, such as Antacids and Warfarin, affecting their efficacy or causing adverse reactions.
- It can be administered orally, intravenously, or topically depending on the infection being treated.
- It can be used in both human and veterinary medicine, though usage guidelines may vary.
- ...
- Example(s):
- Ciprofloxacin, a second-generation fluoroquinolone that is commonly used to treat urinary tract infections and respiratory infections.
- Levofloxacin, a third-generation fluoroquinolone used for treating respiratory and skin infections.
- Moxifloxacin, a fourth-generation fluoroquinolone known for its efficacy against respiratory tract infections.
- ...
- Counter-Example(s):
- Penicillins, which are another class of antibiotics but work by inhibiting bacterial cell wall synthesis.
- Cephalosporins, which are beta-lactam antibiotics and have a different mechanism of action compared to fluoroquinolones.
- See: Antibiotic, Bacterial Infection, Drug Resistance, Quinolone, Quinolone Antibiotic, Ciprofloxacin, Quinolone, Broad-Spectrum Antibiotic, Bacteriocidal, Bicyclic Molecule, 4-Quinolone, Infection, Fluorine, Gram-Negative, Gram-Positive.
References
2024
- (Wikipedia, 2024) ⇒ https://en.wikipedia.org/wiki/Quinolone_antibiotic Retrieved:2024-7-30.
- Quinolone antibiotics constitute a large group of broad-spectrum bacteriocidals that share a bicyclic core structure related to the substance 4-quinolone. They are used in human and veterinary medicine to treat bacterial infections, as well as in animal husbandry, specifically poultry production. Nearly all quinolone antibiotics in use are fluoroquinolones, which contain a fluorine atom in their chemical structure and are effective against both Gram-negative and Gram-positive bacteria. One example is ciprofloxacin, one of the most widely used antibiotics worldwide.