Finasteride
A Finasteride is a synthetic 4-azasteroid compound.
- See: 5α-Reductase Inhibitor, Liver, CYP3A4, Aldehyde Dehydrogenase, Dihydrotestosterone (DHT) Hormone, Pattern Hair Loss, Benign Prostatic Hyperplasia, Hirsutism.
References
2024
- GPT-4
- Finasteride is a synthetic 4-azasteroid compound. As a 4-azasteroid, it belongs to a class of organic compounds that are characterized by a steroid-like structure with a nitrogen atom replacing one of the carbon atoms in the steroid ring system. This structural modification is what gives finasteride its unique pharmacological properties, particularly its ability to inhibit the enzyme 5-alpha-reductase. This enzyme is responsible for converting testosterone into dihydrotestosterone (DHT), a more potent androgen involved in both male pattern hair loss and prostate enlargement
2024
- (Wikipedia, 2024) ⇒ https://en.wikipedia.org/wiki/Finasteride Retrieved:2024-1-16.
- Finasteride, sold under the brand names Proscar and Propecia among others, is a medication used to treat pattern hair loss and benign prostatic hyperplasia (BPH) in men. It can also be used to treat excessive hair growth in women.[1] It is usually taken orally but there are topical formulations for patients with hair loss, designed to minimize systemic exposure by acting specifically on hair follicles.
Finasteride is a 5α-reductase inhibitor and therefore an antiandrogen. It works by decreasing the production of dihydrotestosterone (DHT) by about 70%. In addition to DHT, finasteride also inhibits the production of several anticonvulsant neurosteroids including allopregnanolone, androstanediol, and THDOC. Adverse effects from finasteride are rare; however, some men experience sexual dysfunction, depression, and breast enlargement. In some men, sexual dysfunction may persist after stopping the medication. It may also hide the early symptoms of certain forms of prostate cancer. Finasteride was patented in 1984 and approved for medical use in 1992. It is available as a generic medication. In 2020, it was the 90th-most commonly prescribed medication in the United States, with more than 8million prescriptions.
- Finasteride, sold under the brand names Proscar and Propecia among others, is a medication used to treat pattern hair loss and benign prostatic hyperplasia (BPH) in men. It can also be used to treat excessive hair growth in women.[1] It is usually taken orally but there are topical formulations for patients with hair loss, designed to minimize systemic exposure by acting specifically on hair follicles.
- ↑ Cite error: Invalid
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