Double-Dummy Clinical Trial

A Double-Dummy Clinical Trial is a Crossover Clinical Trial that is Double-Blinded Clinical Trial for retaining the blind when administering supplies.

• Context:
  • It requires that the two treatments cannot be made identical.
• Example(s):
  • a crossover clinical trial in which patients take two sets of treatments: either A (active) and B (placebo), or A (placebo) and B (active). Treatment A is active and indistinguishable placebo; and Treatment B is also active and indistinguishable placebo that are not identical to A.
  • …
• Counter-Example(s):
  • Open-Label Clinical Trial,
  • Placebo-Controlled Clinical Trial,
  • Single-Blinded Clinical Trial,
  • Triple-Blinded Clinical Trial,
  • Music Blind Audition.
• See: Unblinding Clinical Trial Task, Clinical Trial Design, Treatment Group, Control Group, Confirmation Bias, Medical Bias, Clinical Trial Protocol, Good Clinical Practice.

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References

2021

• (Wikipedia, 2021) ⇒ https://en.wikipedia.org/wiki/Glossary_of_clinical_research#D Retrieved:2021-12-18.
  • QUOTE: Double-dummy
    • A technique for retaining the blind when administering supplies in a clinical trial, when the two treatments cannot be made identical. Supplies are prepared for Treatment A (active and indistinguishable placebo) and for Treatment B (active and indistinguishable placebo). Subjects then take two sets of treatment; either A (active) and B (placebo), or A (placebo) and B (active). (ICH E9)

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