Coarse-Grained Confidence Score

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A Coarse-Grained Confidence Score is a confidence score that is a low-ordinal number.



References

2009

  • (Cusick et al., 2009) ⇒ Michael E Cusick, Haiyuan Yu, Alex Smolyar, Kavitha Venkatesan, Anne-Ruxandra Carvunis, Nicolas Simonis, Jean-François Rual, Heather Borick, Pascal Braun, Matija Dreze, Jean Vandenhaute, Mary Galli, Junshi Yazaki, David E Hill, Joseph R Ecker, Frederick P Roth, and Marc Vidal. (2009). “Literature-Curated Protein Interaction Datasets.” In: Nature Methods 6, 39 - 46 (2009)
    • we assigned to each interacting pair an overall score of
      • 0 (no confidence: no mention of the interacting pair, negative answer to the other four questions),
      • 1 (low confidence: interacting pair is mentioned but the interaction is not substantiated by alternative methods) or
      • 2 (high confidence: multiple validations by alternative methods).
    • Two different curators independently curated and scored all interactions. A third independent curator resolved the few scoring conflicts.