Clinical Medicine Phenotype
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A Clinical Medicine Phenotype is a phenotype of a disease.
- Example(s):
- Counter-Example(s):
- See: Asthma, Nosology, Endotype, Chronic Obstructive Pulmonary Disease.
References
2021
- (Wikipedia, 2021) ⇒ https://en.wikipedia.org/wiki/Phenotype_(clinical_medicine) Retrieved:2021-11-2.
- In a nosological sense, the term phenotype can be used in clinical medicine for speaking about the presentation of a disease. The complementary concept in this regard is endotype, which refers to the pathogenesis of the disease ignoring its presentation. In this context, a phenotype would be any observable characteristic or trait of a disease, such as morphology, development, biochemical or physiological properties, or behavior, without any implication of a mechanism. A clinical phenotype would be the presentation of a disease in a given individual. Some organizations have their own specialised meaning. For example, the term 'phenotype' in the field of Chronic obstructive pulmonary disease (COPD) means "a single or combination of disease attributes that describe differences between individuals with COPD as they relate to clinically meaningful outcomes", but nearly all specialities use this meaning in some way, like in asthma research.
2021
- (Wikipedia, 2021) ⇒ https://en.wikipedia.org/wiki/Multiple_sclerosis#Types_and_variants Retrieved:2021-11-2.
- Several phenotypes (commonly termed types), or patterns of progression, have been described. Phenotypes use the past course of the disease in an attempt to predict the future course. They are important not only for prognosis but also for treatment decisions. Currently, the United States National Multiple Sclerosis Society and the Multiple Sclerosis International Federation, describes four types of MS (revised in 2013):
- Clinically isolated syndrome (CIS)
- Relapsing-remitting MS (RRMS)
- Primary progressive MS (PPMS)
- Secondary progressive MS (SPMS)
- Several phenotypes (commonly termed types), or patterns of progression, have been described. Phenotypes use the past course of the disease in an attempt to predict the future course. They are important not only for prognosis but also for treatment decisions. Currently, the United States National Multiple Sclerosis Society and the Multiple Sclerosis International Federation, describes four types of MS (revised in 2013):