Clinical Effectiveness Measure
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A Clinical Effectiveness Measure is a clinical measure for the ability of clinical intervention to achieve a therapeutic effect in the real-world.
- Context:
- It can (typically) be related to Clinical Efficacy.
- It can be evaluated by an Effectiveness Clinical Trial.
- It relates to how well a treatment works in practice, as it can be shown in pragmatic clinical trials.
- …
- Example(s):
- Counter-Example(s):
- See: Clinical Trial, Clinical Trial Phase, Pragmatic Clinical Trial, Explanatory Clinical Trial, Clinical Trial Participant, Clinical Trial Sponsor, Clinical Trial Protocol, Good Clinical Practice, Comparative Effectiveness Research.
References
2021a
- (Wikipedia, 2021) ⇒ https://en.wikipedia.org/wiki/Glossary_of_clinical_research#E Retrieved:2021-12-25.
- QUOTE: Efficacy
- The maximum ability of a drug or treatment to produce a result regardless of dosage. A drug passes efficacy trials if it is effective at the dose tested and against the illness for which it is prescribed. In the procedure mandated by the FDA, Phase II clinical trials gauge efficacy, and Phase III trials confirm it (NLM)
- Effectiveness. In medicine, the ability of an intervention (for example, a drug or surgery) to produce the desired beneficial effect. (NCI)
- QUOTE: Efficacy
2021b
- (Wikipedia, 2021) ⇒ https://en.wikipedia.org/wiki/Effectiveness Retrieved:2021-12-25.
- QUOTE: Effectiveness is the capability of producing a desired result or the ability to produce desired output. When something is deemed effective, it means it has an intended or expected outcome, or produces a deep, vivid impression.
2018
- https://www.gavi.org/vaccineswork/what-difference-between-efficacy-and-effectiveness
- QUOTE: What are the differences between efficacy and effectiveness?
Efficacy is the degree to which a vaccine prevents disease, and possibly also transmission, under ideal and controlled circumstances – comparing a vaccinated group with a placebo group. Effectiveness meanwhile refers to how well it performs in the real world. Although a vaccine that has high efficacy – such as Moderna’s COVID-19 vaccine with 94.5% efficacy and Pfizer’s with 90% efficacy – would be expected to be highly effective in the real world, it is unlikely to translate into the same effectiveness in practice.
- QUOTE: What are the differences between efficacy and effectiveness?