Comparative Effectiveness Research (CER)

A Comparative Effectiveness Research (CER) is a Clinical Research Task that compares health care interventions to determine which treatment work best for which patients and which pose the greatest benefits and harms.

Example(s):
- …
Counter-Example(s):
- Efficacy Clinical Trial,
- Effectiveness Clinical Trial.
See: Good Clinical Practice, Clinical Trial, Pragmatic Clinical Trial, Health Care, Journal of Comparative Effectiveness Research, Institute of Medicine, Cost-Effectiveness Analysis, Incremental Cost-Effectiveness Ratio, Quality-Adjusted Life Year, Randomized Controlled Trial, Clinical Research.

References

(Wikipedia, 2021) ⇒ https://en.wikipedia.org/wiki/Comparative_effectiveness_research Retrieved:2021-12-25.
- Comparative effectiveness research (CER) is the direct comparison of existing health care interventions to determine which work best for which patients and which pose the greatest benefits and harms. The core question of comparative effectiveness research is which treatment works best, for whom, and under what circumstances. Engaging various stakeholders in this process, while difficult, makes research more applicable through providing information that improves patient decision making. The Institute of Medicine committee has defined CER as "the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical condition or to improve the delivery of care. The purpose of CER is to assist consumers, clinicians, purchasers, and policy makers to make informed decisions that will improve health care at both the individual and population levels." Comparative effectiveness research adopts many of the same approaches and methodologies as cost-effectiveness analysis, including the use of incremental cost-effectiveness ratios (ICERs) and quality-adjusted life years (QALYs). An important component of CER is the concept of pragmatic randomised controlled trials. These clinical research trials measure the benefit produced by the treatment in routine clinical practice.