Case-Cohort Study

A Case-Cohort Study is a case controlled study in which the controls are drawn from the same parent cohort (but still are selected before the cases develop).

• Context:
  • It can be analyzed by a Case Cohort Analysis, which may use a Weighted Cox proportional hazards regression model.
  • …
• Counter-Example(s):
  • a Longitudinal Cohort Study.
• See: Controlled Experiment, Cluster Controlled Trial.

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References

2010

• https://onlinecourses.science.psu.edu/stat507/node/50
  • A case-cohort study is similar to a nested case-control study in that the cases and non-cases are within a parent cohort; cases and non-cases are identified at time [math]\displaystyle{ t_1 }[/math], after baseline. In a case-cohort study, the cohort members were assessed for risk factors at any time prior to [math]\displaystyle{ t_1 }[/math]. Non-cases are randomly selected from the parent cohort, forming a subcohort. No matching is performed.

2009

• US National Institute of Health. “IUPAC Glossary of Terms Used in Toxicology."
  • case cohort study: Variant of the case control study in which the controls are drawn from the same cohort as the cases but are identified before the cases develop; some of the controls may later become cases.

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