Argonaute Protein
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An Argonaute Protein is a Protein that ...
- See: RNA-Induced Silencing Complex, Non-Coding RNA, MicroRNA, Piwi-Interacting RNA, Translation, Piwi Domain, Pyrococcus Furiosus, Protein Data Bank, CRISPR.
References
2016
- (Wikipedia, 2016) ⇒ https://en.wikipedia.org/wiki/Argonaute Retrieved:2016-6-6.
- The Argonaute protein family plays a central role in RNA silencing processes, as essential catalytic components of the RNA-induced silencing complex (RISC). RISC complex is responsible for the gene silencing phenomenon known as RNA interference (RNAi). Argonaute proteins bind different classes of small non-coding RNAs, including microRNAs (miRNAs), small interfering RNAs (siRNAs) and Piwi-interacting RNAs (piRNAs). Small RNAs guide Argonaute proteins to their specific targets through sequence complementarity (base pairing), which then leads to mRNA cleavage or translation inhibition.