Single-Blinded Placebo-Controlled Clinical Trial

A Single-Blinded Placebo-Controlled Clinical Trial is a Blined Placebo-Controlled Clinical Trial that is a SingleBlinded Clinical Trial.

• Context:
  • ...
• See: Double-Blinded Placebo-Controlled Clinical Trail, Open-Label Placebo-Controlled Clinical Trail.

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References

2021

• (Baden et al., 2021) ⇒ Lindsey R. Baden, Hana M. El Sahly, Brandon Essink, Karen Kotloff, Sharon Frey, Rick Novak, David Diemert et al. (2021). “Efficacy and Safety of the MRNA-1273 SARS-CoV-2 Vaccine.” New England Journal of Medicine, 384(5).
  • QUOTE: ... This phase 3 randomized, observer-blinded, placebo-controlled trial was conducted at 99 centers across the United States. Persons at high risk for SARS-CoV-2 infection or its complications were randomly assigned in a 1:1 ratio to receive two intramuscular injections of mRNA-1273 (100 μg) or placebo 28 days apart. ...

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