Digital Biomarker

Context:
- It can be challenged by the free-living environment where the movements and mobility are greatly varied and unstructured.
- …
Example(s):
- a Person Falls Counter, e.g. using a Wearable Accelometer.
- a Pulse Oximetry Measure, e.g. to non-invasively monitor oxygen saturation levels.
- …
Counter-Example(s):
- a Molecular Biomarker, such as blood glucose levels.
- a Digital Therapeutic.
See: Digital Medicine.

References

(Coravos et al., 2019) ⇒ Andrea Coravos, Jennifer C. Goldsack, Daniel R. Karlin, Camille Nebeker, Eric Perakslis, Noah Zimmerman, and M. Kelley Erb. (2019). “Digital Medicine: A Primer on Measurement.” Digital Biomarkers 3, no. 2
- QUOTE: ... As a discipline, digital medicine encapsulates both broad professional expertise and responsibilities concerning the use of these digital tools. Digital medicine focuses on evidence generation to support the use of these technologies. Measurement products include digital biomarkers (e.g., using a voice biomarker to track change in tremor for a Parkinson’s patient), electronic clinical outcome assessments (e.g., an electronic patient-reported outcome survey), and tools that measure adherence and safety (e.g., a wearable sensor that tracks falls and smart mirrors for passive monitoring in the home) [5]. Digital measurement products are the focus on this primer. ...

https://www.karger.com/Journal/Details/271954
- QUOTE: ... Digital biomarkers are defined as objective, quantifiable physiological and behavioral data that are collected and measured by means of digital devices such as portables, wearables, implantables, or digestibles. The data collected are typically used to explain, influence, and/or predict health-related outcomes. Digital biomarkers also represent an opportunity to capture clinically meaningful, objective data. ...