Cuzick–Edwards Test

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A Cuzick–Edwards Test is a significance test for detecting clustering of sub-populations within a clustered or non-uniformly distributed general population.



References

2016

The test is based on:
  • using control locations within the general population as the basis of a second or "control" sub-population in addition to the original "case" sub-population;
  • using "nearest-neighbour" analyses to form statistics based on either:
    • the number of other "cases" among the neighbours of each case;
    • the number "cases" which are nearer to each given case than the k-th nearest "control" for that case.
An example application of this test was to spatial clustering of leukaemias and lymphomas among young people in New Zealand.